<Internation Circulation>:Could you please talk about the major difference in anticoagulation strategy between arterial thrombosis and deep vein thrombosis in the clinical practice?

Suzanne Hughes:Arterial thrombosis would typically arise in a patent with atrial fibrillation， with a mural thrombus after a large interior wall infarction， or in a patient with a mechanical heart valve， particularly an aortic mechanical heart valve.  However， a deep vein thrombosis often is a complication of immobilization of following an orthopedic surgery.  So typically patients that require either preventive or therapeutic treatment of a deep vein thrombosis would be on a shorter-term anticoagulation.  Where patients are trying to prevent an arterial thrombosis， they typically have an underlying chronic condition that is going to render them candidates for Warfarin therapy for life rather than short term.